HORDB

ID: hor005845
Uniprot ID: Q17093
Protein name: IWamide
Gene name: NA
Organism: Anemonia sulcata (Mediterranean snakelocks sea anemone)
Family: LWamide neuropeptide family
Source: Animal
Expression: NA
Disease: NA
Comments: NA
Taxonomy: Anemonia (genus), Actiniidae (family), Actiniaria (order), Hexacorallia (subclass), Anthozoa (class), Cnidaria (phylum), Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: NA
GO BP: GO:0007218 neuropeptide signaling pathway
GO CC: GO:0005576 extracellular region

Sequence: ERIGIW
Length: 6(94-99)
Propeptide: KRQQPGLWGRSADPQQAGLWGKRQQPGLWGRSADPQQAGLWGKRQNPGLWGRSADPQQAGLWGKRQHPGLWGRSADPQQAGLWGRSAGSGKRQERIGIWGRSAEPPQYKELEDLKQKSAIPKAKPQ
Signal peptide: NA
Modification: T6 Tryptophan amide
Glycosylation: NA
Mutagenesis: NA

Function: Metamorphosin A may be part of an internal signaling system involved in control of metamorphosis.
Mechanism: NA
Cross BBB: NA
Target: NA
Target Unid: NA
IC50: NA
EC50: NA
ED50: NA
kd: NA
Half life: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor005845_AF2.pdb

hor005845_ESM.pdb

Mass:	86227	Formula:	C36H56N10O9
Absent amino acids:	ACDFHKLMNPQSTVY	Common amino acids:	I
pI:	6.41	Basic residues:	1
Polar residues:	1	Hydrophobic residues:	3
Hydrophobicity:	-5	Boman Index:	-862
Half-Life:	1 hour	Half-Life Yeast:	30 min
Half-Life E.Coli:	>10 hour	Aliphatic Index	130
Instability Index:	-581.67	Extinction Coefficient cystines:	5500
Absorbance 280nm:	1100